Laboratory for Atherosclerosis and Metabolic Research

Laboratory for Atherosclerosis and Metabolic Research

The Laboratory for Atherosclerosis and Metabolic Research has been operating out of the UCDMC for over five years. The laboratory specializes in cardiovascular, metabolic, and diabetic research, covering not only lab-based investigations, but also animal models and clinical studies. Ishwarlal Jialal M.D., Ph.D., PI of the lab, has over 30 years of experience in his field of expertise.

The lab has many areas of interest. Some of the more prominent fields of interest include: C-reactive Protein, Biomarkers of Oxidative Stress and Inflammation, Monocyte Biology, Diabetic complications and Dyslipidemias and therapeutic modulation. The lab utilizes many cutting edge technologies in cell and molecular biology, animal models, clinical studies and thus translational research. Some of the instrumentation include HPLC, GC, BD FACS Array, Ultracentrifuge, Spectrofluorometer etc.

These technologies are combined with a wide variety of clinical research studies that allow the researchers to observe conditions both in-vitro and in-vivo. Studies currently underway involve therapeutic lifestyle changes, Aloe vera, Sterols, and the relationship with Dyslipidemia, Heart Disease and Diabetes and its complications.